This directory contains alignments of the following assemblies: - target/reference: Garter snake (thaSir1, Jun. 2015 (Thamnophis_sirtalis-6.0/thaSir1), The Genome Institute at Washington University School of Medicine (WUGSC)) - query: Chicken (galGal6, Mar. 2018 (GRCg6a/galGal6), Genome Reference Consortium) Files included in this directory: - md5sum.txt: md5sum checksums for the files in this directory - thaSir1.galGal6.all.chain.gz: chained lastz alignments. The chain format is described in http://genome.ucsc.edu/goldenPath/help/chain.html . - thaSir1.galGal6.net.gz: "net" file that describes rearrangements between the species and the best Chicken match to any part of the Garter snake genome. The net format is described in http://genome.ucsc.edu/goldenPath/help/net.html . - thaSir1.galGal6.net.axt.gz: chained and netted alignments, i.e. the best chains in the Garter snake genome, with gaps in the best chains filled in by next-best chains where possible. The axt format is described in http://genome.ucsc.edu/goldenPath/help/axt.html . - thaSir1.galGal6.synNet.maf.gz - filtered net file for syntenic alignments only, in MAF format, see also, description of MAF format: http://genome.ucsc.edu/FAQ/FAQformat.html#format5 - thaSir1.galGal6.syn.net.gz - filtered net file for syntenic alignments only - reciprocalBest/ directory, contains reciprocal-best netted chains for thaSir1-galGal6 The chainSwap program was used to translate galGal6-referenced chained lastz alignments to thaSir1 into thaSir1-referenced chains aligned to galGal6. See the download directory goldenPath/galGal6/vsThaSir1/README.txt for more information about the galGal6-referenced lastz and chaining process. Chained alignments were processed into nets by the chainNet, netSyntenic, and netClass programs. Best-chain alignments in axt format were extracted by the netToAxt program. All programs run after lastz were written by Jim Kent at UCSC. ---------------------------------------------------------------- If you plan to download a large file or multiple files from this directory, we recommend you use ftp rather than downloading the files via our website. To do so, ftp to hgdownload.soe.ucsc.edu, then go to the directory goldenPath/thaSir1/vsGalGal6/. To download multiple files, use the "mget" command: mget <filename1> <filename2> ... - or - mget -a (to download all files in the current directory) All files in this directory are freely available for public use. -------------------------------------------------------------------- References Harris, R.S. (2007) Improved pairwise alignment of genomic DNA Ph.D. Thesis, The Pennsylvania State University Chiaromonte F, Yap VB, Miller W. Scoring pairwise genomic sequence alignments. Pac Symp Biocomput. 2002:115-26. Kent WJ, Baertsch R, Hinrichs A, Miller W, Haussler D. Evolution's cauldron: Duplication, deletion, and rearrangement in the mouse and human genomes. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11484-9. Schwartz S, Kent WJ, Smit A, Zhang Z, Baertsch R, Hardison RC, Haussler D, Miller W. Human-Mouse Alignments with BLASTZ. Genome Res. 2003 Jan;13(1):103-7.
Name Last modified Size Description
Parent Directory - reciprocalBest/ 2018-10-27 03:24 - md5sum.txt 2018-10-27 00:22 306 thaSir1.galGal6.syn.net.gz 2018-10-27 00:21 6.4M thaSir1.galGal6.net.gz 2018-10-27 00:19 20M thaSir1.galGal6.synNet.maf.gz 2018-10-27 00:22 31M thaSir1.galGal6.all.chain.gz 2018-10-27 00:11 39M thaSir1.galGal6.net.axt.gz 2018-10-27 00:17 82M