This directory contains alignments of the C. briggsae assembly (cb1, Jul. 2002, assembly version cb25.agp8) to the C. elegans assembly (ce2, Mar. 2004, Release WS120). Files included in this directory: - axtChrom.zip: contains the axt alignments generated by blastz. Blastz output was converted to lav format, which was then converted to axt format. - axtNetCb1.zip: contains chained and netted alignments, i.e. the best chains in the genome, with gaps in the best chains filled in by next-best chains where possible. - cb1.chain.zip: chained blastz alignments. The chain format is described in http://genome.ucsc.edu/goldenPath/help/chain.html. - cb1.net.zip: "net" file that describes rearrangements between the species and the best C. briggsae match to any part of the C. elegans genome. The net format is described in http://genome.ucsc.edu/goldenPath/help/net.html. - md5sum.txt: checksums of the files in this directory The alignments in the axtChrom and axtNet directories are in "axt" format. For a description, see http://genome.ucsc.edu/goldenPath/help/axt.html. The alignments were produced by the blastz alignment program, which is available from Webb Miller's lab at Penn State University (http://www.bx.psu.edu/miller_lab/). The blastz scoring matrix used was: A C G T A 91 -114 -31 -123 C -114 100 -125 -31 G -31 -125 100 -114 T -123 -31 -114 91 with a gap open penalty of 400 and a gap extension penalty of 30. The minimum score for an alignment to be kept was 3000 for the first pass and 2200 for the second pass, which restricted the search space to the regions between two alignments found in the first pass. The .lav format blastz output, which does not include the sequence, was converted to .axt with lavToAxt -dropSelf, which excises alignment blocks along the diagonal. The axtNet alignments were processed with chainNet, netSyntenic, and netClass written by Jim Kent at UCSC. ----------------------------------------------------------------- If you plan to download a large file or multiple files from this directory, we recommend you use ftp rather than downloading the files via our website. To do so, ftp to hgdownload.cse.ucsc.edu, then go to the directory goldenPath/ce2/vsCb1. To download multiple files, use the "mget" command: mget <filename1> <filename2> ... - or - mget -a (to download all the files in the directory) All the files in this directory are freely available for public use.
Name Last modified Size Description
Parent Directory - axtChrom.zip 2004-05-07 18:03 117M axtNetCb1.zip 2004-05-07 18:03 32M cb1.chain.zip 2004-05-07 18:03 36M cb1.net.zip 2004-05-07 18:03 7.5M md5sum.txt 2004-05-07 18:07 189