Description
This track shows Evolutionary Conserved Regions computed by the
Exofish (Roest et al., 2000) program at Genoscope.
Each singleton block corresponds to an "ecore"; two blocks connected by a thin line
correspond to an "ecotig", a set of colinear ecores in a syntenic region.
Methods
Genome-wide sequence comparisons were done at the protein-coding level between the genome sequences
of the fruitfly, Drosophila melanogaster and the mosquito, Anopheles gambiae to
detect evolutionarily conserved regions (ECORES). See Jaillon et al., 2003.
The sequence versions used in the comparison were
Ensembl Drosophila v.16.3a.1 (Jan. 2003, the same as BDGP Release 3.1
used by the UCSC Genome Browser) and
Ensembl Anopheles v.16.2.1 .
Credits
Thanks to Olivier Jaillon at Genoscope for contributing the data.
References
Jaillon O, Dossat C, Eckenberg R, Eiglmeier K, Segurens B, Aury JM, Roth CW, Scarpelli C, Brey PT,
Weissenbach J et al.
Assessing the Drosophila melanogaster and Anopheles gambiae genome annotations using genome-wide
sequence comparisons.
Genome Res. 2003 Jul;13(7):1595-9.
PMID: 12840038; PMC: PMC403732
Roest Crollius H, Jaillon O, Bernot A, Dasilva C, Bouneau L, Fischer C, Fizames C, Wincker P,
Brottier P, Quétier F et al.
Estimate of human gene number provided by genome-wide analysis using Tetraodon nigroviridis DNA
sequence.
Nat Genet. 2000 Jun;25(2):235-8.
PMID: 10835645