Description

This track displays variants identified by Gire et al. in 81 isolates from the 2014 strain of Ebola virus (78 from Sierra Leone and 3 from Guinea) that are specific to the 2014 strain. At least one 2014 isolate carries a base not found elsewhere in the EBOV alignment.

Display Conventions

Items are labeled by ancestral nucleotide and 2014-derived nucleotide. Non-coding variants are black, synonymous variants are green, and missense variants are red and also labeled by gene and amino acid change. Click on an item to view more details such as the derived allele frequency in 2014 isolates and, for missense changes, the BLOSUM62 substitution score.

Reference

Gire SK, Goba A, Andersen KG, Sealfon RS, Park DJ, Kanneh L, Jalloh S, Momoh M, Fullah M, Dudas G et al. Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak. Science 2014 Sep 12;345(6202):1369-72. PMID: 25214632